fibrosis Archives - Well Referenced

New Therapeutic Approach to Heart Failure Due to Myocardial Infarction Based on Targeting Growth Hormone-Releasing Hormone Receptor

This 2015 preclinical study by Kanashiro-Takeuchi et al. investigated the effects of growth hormone-releasing hormone (GHRH) agonists on myocardial infarction (MI)-induced heart failure. Using rodent models, the researchers administered GHRH agonists (JI-38, MR-356, and MR-409) and observed significant improvements in cardiac function, including reduced infarct size, enhanced vascular density, increased

June 26, 2025 No Comments

Targeting aging and age-related diseases with vaccines

This 2024 review explores the potential of vaccines to address aging and associated chronic diseases. It discusses strategies targeting specific antigens linked to conditions such as Alzheimer’s disease, type II diabetes, hypertension, abdominal aortic aneurysm, atherosclerosis, osteoarthritis, fibrosis, and cancer. Additionally, the article examines emerging vaccines aimed at eliminating senescent

June 26, 2025 No Comments

Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts

The study titled “Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts” (Arthritis Research & Therapy, 2014, PMID: 25123250) explores the role of lipoic acid (LA) and its active metabolite, dihydrolipoic acid (DHLA), in systemic sclerosis (SSc), a disease characterized by fibrosis of the skin and

June 26, 2025 No Comments

Tag: fibrosis

New Therapeutic Approach to Heart Failure Due to Myocardial Infarction Based on Targeting Growth Hormone-Releasing Hormone Receptor

Targeting aging and age-related diseases with vaccines

Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts