Melatonin for the prevention and treatment of cancer

This 2017 review explores melatonin's potential as a preventive and therapeutic agent against various cancers, including breast, prostate, gastric, and colorectal cancers. Melatonin exhibits multiple anticancer mechanisms: it acts as a potent antioxidant, modulates MT1 and MT2 melatonin receptors, induces apoptosis, regulates pro-survival signaling pathways and tumor metabolism, inhibits angiogenesis