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Tag: melatonin receptors

Melatonin as a treatment for gastrointestinal cancer: a review

This 2015 review examines melatonin’s potential as a therapeutic agent against gastrointestinal (GI) cancers. It highlights the association between disrupted melatonin rhythms and increased GI cancer risk, as evidenced by epidemiological and experimental studies. Melatonin’s anticancer mechanisms include inhibition of cell proliferation, invasion, metastasis, and angiogenesis, as well as promotion

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June 26, 2025 No Comments

Melatonin for the prevention and treatment of cancer

This 2017 review explores melatonin’s potential as a preventive and therapeutic agent against various cancers, including breast, prostate, gastric, and colorectal cancers. Melatonin exhibits multiple anticancer mechanisms: it acts as a potent antioxidant, modulates MT1 and MT2 melatonin receptors, induces apoptosis, regulates pro-survival signaling pathways and tumor metabolism, inhibits angiogenesis

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June 26, 2025 No Comments