L-carnosine and its Derivatives as New Therapeutic Agents for the Prevention and Treatment of Vascular Complications of Diabetes

This review explores the potential of L-carnosine and its carnosinase-resistant derivatives in preventing and treating vascular complications in diabetes. L-carnosine acts as a scavenger of reactive carbonyl species (RCS), helping to reduce the formation of harmful advanced glycation end-products (AGEs) and advanced lipoxidation end-products (ALEs), both of which contribute to