Well Referenced

Tag: Metabolic Syndrome

Traditional Chinese Medicine in Treatment of Metabolic Syndrome

This comprehensive review explores the role of Traditional Chinese Medicine (TCM) in managing metabolic syndrome (MetS). It introduces TCM principles and evaluates 25 traditional Chinese herbs for their potential therapeutic effects on MetS components, including obesity, insulin resistance, dyslipidemia, and hypertension. Notably, ginseng (Panax ginseng and Panax quinquefolium) exhibits anti-hyperglycemic,

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June 26, 2025 No Comments

A Pilot Study Investigating the Effect of Caralluma Fimbriata Extract on the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomised Controlled Clinical Trial

This 12-week randomized, double-blind, placebo-controlled clinical trial assessed the effects of Caralluma fimbriata extract on metabolic syndrome risk factors in 33 overweight and obese adults. Participants received 1 g/day of Caralluma fimbriata extract or placebo, alongside controlled dietary intake and physical activity. The Caralluma group experienced a greater reduction in

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June 26, 2025 No Comments

Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial

This 2019 randomized cross-over trial investigated the effects of a whole grain-rich diet compared to a refined grain diet on body weight, systemic inflammation, and gut microbiome composition in 60 Danish adults at risk of metabolic syndrome. Participants underwent two 8-week dietary intervention periods, separated by a washout period of

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June 26, 2025 No Comments

Association of vitamin B12 with obesity, overweight, insulin resistance and metabolic syndrome, and body fat composition; primary care-based study

This 2013 cross-sectional study assessed 976 adults (414 obese, 212 overweight, 351 controls) in a primary care setting to examine the relationship between vitamin B12 levels and metabolic parameters. Findings revealed significantly lower vitamin B12 levels in obese (178.9 ± 25.2 pg/mL) and overweight (219.8 ± 78.5 pg/mL) individuals compared

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June 26, 2025 No Comments

Metabolic and cardiovascular adverse effects associated with antipsychotic drugs

This 2011 review highlights the significant metabolic and cardiovascular risks associated with antipsychotic medications, particularly second-generation antipsychotics like clozapine and olanzapine. These drugs are linked to weight gain, hyperglycemia, dyslipidemia, and metabolic syndrome, increasing the risk of type 2 diabetes and cardiovascular disease. The exact mechanisms remain unclear but may

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June 26, 2025 No Comments

Association of Prescription H1 Antihistamine Use With Obesity: Results From the National Health and Nutrition Examination Survey

This 2010 study analyzed data from the 2005–2006 NHANES to investigate the relationship between prescription H1 antihistamine use and obesity in adults. The analysis included 268 antihistamine users and 599 matched controls. Findings revealed that antihistamine users had significantly higher body weight, BMI, waist circumference, and insulin concentrations compared to

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June 26, 2025 No Comments

Schizophrenia Treatment with Second-Generation Antipsychotics: A Multi-Country Comparison of the Costs of Cardiovascular and Metabolic Adverse Events and Weight Gain

This 2021 study conducted a multi-country economic analysis to assess the financial impact of cardiovascular and metabolic adverse events, including weight gain, associated with second-generation antipsychotics (SGAs) in the treatment of schizophrenia. The research highlighted that SGAs, while effective in managing schizophrenia symptoms, are linked to significant metabolic side effects

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June 26, 2025 No Comments

Testosterone and metabolic syndrome

This review explores the complex relationship between testosterone levels and metabolic syndrome (MetS) in men. Low total testosterone (TT) and sex hormone-binding globulin (SHBG) levels are commonly observed in men with MetS, primarily due to hyperinsulinemia and increased inflammatory cytokines associated with obesity. Low SHBG levels have been identified as

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June 26, 2025 No Comments