Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approach

This 2022 review article published in International Immunopharmacology (DOI: 10.1016/j.intimp.2022.109130) provides a comprehensive overview of Interleukin-6 (IL-6), a key cytokine involved in both immune regulation and immune dysregulation. IL-6 plays a central role in inflammation, B and T cell activity, acute-phase responses, and is pivotal in autoimmune and chronic inflammatory