This 2023 systematic review and meta-analysis evaluated 26 randomized controlled trials involving 1,691 women with polycystic ovary syndrome (PCOS) to assess the efficacy and safety of inositol supplementation. Inositol significantly increased the likelihood of menstrual cycle normalization compared to placebo (risk ratio: 1.79; 95% CI: 1.13–2.85) and was non-inferior to
