Coenzyme Q10 supplementation alleviates pain in pregabalin-treated fibromyalgia patients via reducing brain activity and mitochondrial dysfunction

This clinical trial investigated the effects of Coenzyme Q10 (CoQ10) supplementation on pain reduction in fibromyalgia patients receiving pregabalin. The study found that adding CoQ10 to pregabalin therapy significantly reduced pain, improved mitochondrial function, and decreased brain hyperactivity, suggesting a synergistic effect in managing fibromyalgia symptoms. CoQ10, a key component