Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause

This meta-analysis highlights the benefits of hormone replacement therapy (HRT) for women aged 50-59, within 10 years of menopause. HRT is shown to reduce coronary heart disease, lower all-cause mortality, and alleviate osteoporosis without significant risks like breast cancer in younger women. It suggests that early-stage HRT may be a