Hormone-brain-aging relationships, broadly reactive with imidazole-containing dipeptides: targeting of telomere attrition as an aging biomarker and dynamic telomerase activity flirting

This 2015 review explores the potential of imidazole-containing dipeptides, such as carnosine and carcinine, in modulating telomere dynamics and telomerase activity to counteract cellular aging. The authors propose that these compounds may influence hormone-brain-aging interactions by affecting neurotransmission and oxidative stress pathways. Preliminary studies suggest that supplementation with these dipeptides