This systematic review and meta-analysis published in Biomed Research International investigates the relationship between serum interleukins (IL-1β, IL-2, IL-4, IL-6, IL-8, and IL-10) and the severity of COVID-19. The study, involving 14,136 participants from 61 studies, found that elevated interleukin levels, particularly IL-6, IL-8, and IL-10, were associated with more