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Tag: IL-10

Effect of Plant Extracts Combinations on TNF-α, IL-6 and IL-10 Levels in Serum of Rats Exposed to Acute and Chronic Stress

This animal study investigated the effects of two plant extract combinations, Antistress I and Antistress II, on cytokine levels in rats exposed to acute and chronic stress. The results showed that both combinations reduced pro-inflammatory cytokines (TNF-α and IL-6) and modulated the anti-inflammatory cytokine IL-10, with Antistress II having the

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June 26, 2025 No Comments

Associations between Serum Interleukins (IL-1 β, IL-2, IL-4, IL-6, IL-8, and IL-10) and Disease Severity of COVID-19: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis published in Biomed Research International investigates the relationship between serum interleukins (IL-1β, IL-2, IL-4, IL-6, IL-8, and IL-10) and the severity of COVID-19. The study, involving 14,136 participants from 61 studies, found that elevated interleukin levels, particularly IL-6, IL-8, and IL-10, were associated with more

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June 26, 2025 No Comments

Methylene blue attenuates neuroinflammation after subarachnoid hemorrhage in rats through the Akt/GSK-3β/MEF2D signaling pathway

This study evaluated the neuroprotective effects of methylene blue (MB) in rats following subarachnoid hemorrhage (SAH), focusing on its ability to reduce neuroinflammation. MB treatment significantly decreased brain edema and improved neurological function by activating the Akt/GSK-3β/MEF2D signaling pathway, which led to increased nuclear MEF2D levels. Additionally, MB reduced pro-inflammatory

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June 26, 2025 No Comments