This 2018 review article published in Advances in Experimental Medicine and Biology (DOI: 10.1007/978-3-030-25650-0_3, PMID: 31493221) explores various aging biomarkers, such as telomeres, longevity proteins, senescence-associated secretory phenotypes, and gut microbiota, while assessing their potential as therapeutic targets for anti-aging interventions. The review highlights how these biomarkers are linked to