This 2012 non-systematic review explores the relationship between obesity and accelerated aging, focusing on telomere dynamics in adipose tissue. Telomeres, protective DNA-protein structures at chromosome ends, shorten with each cell division, a process exacerbated by oxidative stress. The review highlights that shorter telomeres are associated with higher body mass index
This 2012 review and in vitro/animal study explored the critical role of magnesium (Mg) in slowing aging processes, with a focus on insights from space flight research, where microgravity-induced Mg depletion accelerates aging. Findings indicate that Mg deficiency contributes to elevated catecholamines, oxidative stress, insulin resistance, inflammation, endothelial damage, and
This 2018 review article published in Advances in Experimental Medicine and Biology (DOI: 10.1007/978-3-030-25650-0_3, PMID: 31493221) explores various aging biomarkers, such as telomeres, longevity proteins, senescence-associated secretory phenotypes, and gut microbiota, while assessing their potential as therapeutic targets for anti-aging interventions. The review highlights how these biomarkers are linked to
