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Tag: VTE

Testosterone replacement therapy and the risk of venous thromboembolism: A systematic review and meta-analysis of randomized controlled trials

This 2021 systematic review and meta-analysis evaluated the association between testosterone replacement therapy (TRT) and venous thromboembolism (VTE) risk by analyzing 13 randomized controlled trials encompassing 5,050 men. The pooled data indicated no significant increase in VTE risk among men receiving TRT compared to placebo (RR: 1.03; 95% CI: 0.49–2.14;

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June 26, 2025 No Comments

Use of hormone replacement therapy and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases

This 2019 nested case-control study analyzed data from the QResearch and CPRD databases to assess the association between hormone replacement therapy (HRT) use and the risk of venous thromboembolism (VTE) in women aged 40–79. The study found that oral HRT, particularly combined estrogen-progestogen formulations, was associated with a significantly increased

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June 26, 2025 No Comments