Well Referenced

Tag: overweight

Supplementation of green coffee bean extract in healthy overweight subjects increases lean mass/fat mass ratio: A randomized, double-blind clinical study

This 2021 randomized, double-blind, placebo-controlled clinical trial evaluated the effects of daily supplementation with 500 mg of CGA-7™, a standardized green coffee bean extract rich in chlorogenic acid isomers, over 12 weeks in 71 healthy overweight adults (BMI 25–30 kg/m²). The CGA-7 group showed significant reductions in body weight, BMI,

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June 26, 2025 No Comments

Association of vitamin B12 with obesity, overweight, insulin resistance and metabolic syndrome, and body fat composition; primary care-based study

This 2013 cross-sectional study assessed 976 adults (414 obese, 212 overweight, 351 controls) in a primary care setting to examine the relationship between vitamin B12 levels and metabolic parameters. Findings revealed significantly lower vitamin B12 levels in obese (178.9 ± 25.2 pg/mL) and overweight (219.8 ± 78.5 pg/mL) individuals compared

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June 26, 2025 No Comments

Calcium plus Vitamin D3 Supplementation Facilitated Fat Loss in Overweight and Obese College Students

This 12-week open-label, randomized controlled trial investigated the effects of calcium (600 mg/day) and vitamin D3 (125 IU/day) supplementation on body composition in 53 overweight and obese college students with very low habitual calcium intake. All participants followed a 500 kcal/day energy-restricted diet. The calcium+D group experienced significantly greater reductions

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June 26, 2025 No Comments

Vital Signs: Trends in Incidence of Cancers Associated with Overweight and Obesity – United States, 2005–2014

This 2017 CDC report analyzed U.S. cancer registry data from 2005 to 2014, focusing on 13 cancers linked to overweight and obesity, including postmenopausal breast, colorectal, endometrial, pancreatic, and liver cancers. In 2014, approximately 631,000 cases (40% of all cancers) were associated with excess body weight. Incidence rates were higher

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June 26, 2025 No Comments

Gut Microbiota Richness and Composition and Dietary Intake of Overweight Pregnant Women Are Related to Serum Zonulin Concentration, a Marker for Intestinal Permeability

This cross-sectional study of 100 overweight pregnant women found that lower serum zonulin concentrations—an indicator of improved intestinal barrier function—were associated with greater gut microbiota richness, higher dietary intakes of n-3 polyunsaturated fatty acids (PUFAs), fiber, vitamins, and minerals, and specific gut bacterial taxa. The findings suggest that promoting dietary

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June 26, 2025 No Comments

Anthropometric and cardiometabolic effects of polyphenols in people with overweight and obesity: an umbrella review

This umbrella review analyzes the effects of polyphenols on anthropometric measures and cardiometabolic risk factors in individuals with overweight and obesity. Polyphenol supplementation led to significant reductions in body weight, body mass index (BMI), waist circumference, and fasting blood glucose levels. Additionally, improvements were seen in cholesterol levels, blood pressure,

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June 26, 2025 No Comments

Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans

This randomized controlled trial published in Diabetologia (2015) examined the effects of combined resistance and aerobic exercise training on insulin sensitivity, branched-chain amino acid (BCAA) metabolism, and glycine levels in overweight adults. Over a 6-month period, sedentary participants with a BMI ≥25 (n=119) followed a supervised exercise protocol. The study

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June 26, 2025 No Comments

The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients

This randomized controlled trial examined the effects of Coenzyme Q10 (CoQ10) supplementation on inflammatory and endothelial dysfunction markers in overweight and obese women with Polycystic Ovary Syndrome (PCOS). Over 8 weeks, CoQ10 significantly reduced levels of TNF-α, hs-CRP, IL-6, VCAM-1, and E-selectin, indicating improved inflammatory status and vascular function, although

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June 26, 2025 No Comments

Effects of Oral Magnesium Supplementation on Insulin Sensitivity and Blood Pressure in Normo-Magnesemic Nondiabetic Overweight Korean Adults

The study titled “Effects of oral magnesium supplementation on insulin sensitivity and blood pressure in normo-magnesemic nondiabetic overweight Korean adults” examined the effects of daily magnesium supplementation (300 mg as magnesium oxide) over 12 weeks in 155 overweight Korean adults with normal magnesium levels. This randomized, double-blind, placebo-controlled trial found

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June 26, 2025 No Comments