Well Referenced

Tag: lumbar disc herniation

Comparative evaluation of oxygen-ozone therapy and combined use of oxygen-ozone therapy with percutaneous intradiscal radiofrequency thermocoagulation for the treatment of lumbar disc herniation

This randomized controlled trial compared the effectiveness of oxygen-ozone therapy alone versus a combination of oxygen-ozone therapy and percutaneous intradiscal radiofrequency thermocoagulation (PIRFT) for the treatment of lumbar disc herniation. The study showed that both treatments significantly reduced pain and disability, but the combination therapy (ozone-PIRFT) led to superior outcomes

Read More »
June 26, 2025 No Comments

Efficacy of Intradiscal Ozone Therapy with or without Periforaminal Steroid Injection on Lumbar Disc Herniation: A Double-Blinded Controlled Study

This randomized controlled trial evaluated the effectiveness of intradiscal ozone therapy, with or without periforaminal steroid injection, in treating lumbar disc herniation (LDH) and associated low back and leg pain. The study included 65 patients who were divided into two groups: one received only ozone therapy, and the other received

Read More »
June 26, 2025 No Comments

Intradiscal oxygen-ozone chemonucleolysis versus microdiscectomy for lumbar disc herniation radiculopathy: a non-inferiority randomized control trial

This randomized controlled trial compared intradiscal oxygen-ozone chemonucleolysis (O2-O3) with microdiscectomy in treating lumbar disc herniation radiculopathy. The study showed that O2-O3 therapy was non-inferior to microdiscectomy in reducing pain and improving function, making it an effective, less invasive alternative to surgery. Both treatments resulted in significant patient improvement, with

Read More »
June 26, 2025 No Comments

Intramuscular oxygen-ozone therapy in the treatment of acute back pain with lumbar disc herniation: a multicenter, randomized, double-blind, clinical trial of active and simulated lumbar paravertebral injection

This randomized controlled trial investigates the use of intramuscular oxygen-ozone (O2O3) therapy in treating acute low back pain (LBP) due to lumbar disc herniation. The study included 60 participants, with those receiving active O2O3 therapy showing significant improvements in pain reduction, disability, and reliance on pain medication compared to the

Read More »
June 26, 2025 No Comments

Ozone therapy in musculoskeletal medicine: a comprehensive review

This 2024 comprehensive review titled “Ozone therapy in musculoskeletal medicine: a comprehensive review” (European Journal of Medical Research, DOI: [10.1186/s40001-024-01976-4*) evaluated the use of ozone therapy in treating musculoskeletal conditions such as osteoarthritis, lumbar disc herniation, tendinopathies, and myofascial pain syndromes. The review described ozone’s mechanisms—enhancing oxygen metabolism, modulating oxidative

Read More »
June 26, 2025 No Comments

Sciatica: treatment with intradiscal and intraforaminal injections of steroid and oxygen-ozone versus steroid only

This 2007 randomized controlled trial titled “Sciatica: Treatment with Intradiscal and Intraforaminal Injections of Steroid and Oxygen-Ozone versus Steroid Only” (Radiology, DOI: [10.1148/radiol.2423051934*) compared the effectiveness of standard steroid/anesthetic injections with and without the addition of oxygen-ozone (O₂-O₃) therapy in 159 patients suffering from radicular pain due to acute lumbar

Read More »
June 26, 2025 No Comments

The Effect of Paravertebral Ozone Injection in the Treatment of Low Back Pain

This 2019 retrospective observational study titled “The Effect of Paravertebral Ozone Injection in the Treatment of Low Back Pain” (Pain Practice, DOI: [10.1111/papr.12812*) evaluated the impact of paravertebral ozone/oxygen injections on 62 patients with chronic low back pain. Patients received 50 mL of a 15 µg/mL ozone mixture weekly for

Read More »
June 26, 2025 No Comments

Treatment of the lumbar disc herniation with intradiscal and intraforaminal injection of oxygen-ozone

This 2013 randomized controlled trial titled “Treatment of the Lumbar Disc Herniation with Intradiscal and Intraforaminal Injection of Oxygen-Ozone” (Journal of Back and Musculoskeletal Rehabilitation, DOI: [10.3233/BMR-130386]*) assessed the effectiveness of oxygen-ozone injections with or without steroids in 172 patients suffering from lumbar disc herniation and radicular pain. Both groups—oxygen-ozone

Read More »
June 26, 2025 No Comments