Well Referenced

Tag: libido

Treatment of Diabetic Impotence with Umbilical Cord Blood Stem Cell Intracavernosal Transplant: Preliminary Report of 7 Cases

This 2010 pilot study assessed the safety and efficacy of intracavernosal injections of human umbilical cord blood stem cells (hUCBSCs) in seven male patients (ages 57–87) with type 2 diabetes mellitus and refractory erectile dysfunction (ED). Each patient received a single injection of 1.5×10⁷ hUCBSCs without immunosuppression. Over a 9-month

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June 26, 2025 No Comments

Female sexual dysfunction: focus on low desire

This 2015 review article examines hypoactive sexual desire disorder (HSDD), the most prevalent form of female sexual dysfunction, particularly among midlife women. It explores the multifactorial etiology encompassing biological, psychological, and social factors, including health status, depression, medications, relationship dissatisfaction, and history of abuse. The article discusses the transition from

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June 26, 2025 No Comments

Effects of Oral Contraceptives on Sexual Behavior

This 1976 review article by J. Cohen examines the impact of oral contraceptives on various aspects of women’s sexual behavior. The study found that 34–54% of women reported an increase in the frequency of sexual relations, while 32% experienced improved orgasm. However, 5–6% of women in rigorous studies reported frigidity,

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June 26, 2025 No Comments

Prospective randomized study of sexual function in men taking dutasteride for the treatment of androgenetic alopecia

This 2018 randomized controlled trial evaluated sexual adverse events in 117 men aged 23–50 receiving dutasteride 0.5 mg daily for androgenetic alopecia. During the 24-week double-blind phase, sexual adverse events (impotence, decreased libido, ejaculation disorders) occurred in 16% of the dutasteride group versus 8% in the placebo group. In the

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June 26, 2025 No Comments

Testosterone therapy improves well being and psychological health

This review evaluates the impact of testosterone therapy (TTh) on psychological health and overall well-being in men with symptomatic hypogonadism. Evidence indicates that TTh can lead to modest yet consistent improvements in mood, energy levels, libido, and cognitive function. These benefits are particularly relevant for men experiencing fatigue, depression, and

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June 26, 2025 No Comments

The Role of Androgens in Female Sexual Dysfunction

This 2004 review by Jan L. Shifren explores the multifactorial causes of female sexual dysfunction (FSD), emphasizing the emerging recognition of androgen deficiency as a contributing factor. While psychological, relational, and physiological issues are primary considerations, low androgen levels—due to aging, oophorectomy, adrenal insufficiency, or hypopituitarism—may lead to decreased libido

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June 26, 2025 No Comments

Hyperprolactinemia and sexual function in men: a short review

This 2003 review examines the impact of hyperprolactinemia (HPRL) on male sexual function. HPRL is associated with decreased libido, erectile dysfunction, and ejaculatory disorders. While traditionally attributed to reduced testosterone levels, evidence suggests that prolactin may also exert direct effects on central neurotransmitter systems, influencing sexual function independently of testosterone.

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June 26, 2025 No Comments

Effects of Saffron (Crocus sativus) on Sexual Dysfunction Among Men and Women: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis evaluated the efficacy of saffron (Crocus sativus) in treating sexual dysfunction across genders. Analyzing five randomized controlled trials encompassing 173 participants, the study found that saffron significantly improved overall sexual dysfunction (standardized mean difference [SMD] = 0.811; 95% CI: 0.356–1.265) and its subdomains (SMD =

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June 26, 2025 No Comments

Effect of Lepidium meyenii (MACA) on Sexual Desire and Its Absent Relationship with Serum Testosterone Levels in Adult Healthy Men

This 12-week double-blind, placebo-controlled, randomized trial investigated the effects of gelatinized maca (Lepidium meyenii) on sexual desire and hormone levels in 57 healthy men aged 21–56. Participants received either 1,500 mg or 3,000 mg of maca daily or a placebo. Self-perception of sexual desire was assessed at 4, 8, and

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June 26, 2025 No Comments

Influence of a Specialized Trigonella foenum-graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study

This double-blind, randomized, placebo-controlled study evaluated the effects of a standardized Trigonella foenum-graecum (fenugreek) seed extract (Libifem) on sex hormones and sexual function in 80 healthy menstruating women aged 20–49 years with self-reported low sexual desire. Participants received 600 mg/day of Libifem or placebo over two menstrual cycles. Outcomes included

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June 26, 2025 No Comments