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Tag: IIEF-EF

Penile low intensity shock wave treatment for PDE5I refractory erectile dysfunction: a randomized double-blind sham-controlled clinical trial

This randomized, double-blind, sham-controlled clinical trial assessed the efficacy of low-intensity extracorporeal shockwave therapy (LI-ESWT) in 76 men with vascular erectile dysfunction (ED) unresponsive to phosphodiesterase type 5 inhibitors (PDE5Is). Participants received weekly sessions for four weeks (5000 shocks/session at 0.09 mJ/mm²). At 3 months, the treatment group showed a

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June 26, 2025 No Comments

Effectiveness and Safety of Intracavernosal IncobotulinumtoxinA (Xeomin®) 100 U as an Add-on Therapy to Standard Pharmacological Treatment for Difficult-to-Treat Erectile Dysfunction: A Case Series

This 2022 case series evaluated the safety and efficacy of intracavernosal injection (ICI) of incobotulinumtoxinA (Xeomin®) 100 U as an adjunct to standard pharmacological treatments (PDE5 inhibitors or PGE1 ICIs) in 66 men with difficult-to-treat erectile dysfunction (ED). Approximately 52% of patients achieved a clinically meaningful improvement in International Index

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June 26, 2025 No Comments

The Efficacy of Li-ESWT Combined With VED in Diabetic ED Patients Unresponsive to PDE5is: A Single-Center, Randomized Clinical Trial

This 2022 randomized clinical trial assessed the efficacy of combining low-intensity extracorporeal shock wave therapy (Li-ESWT) with vacuum erectile device (VED) therapy in 105 diabetic men with erectile dysfunction (ED) unresponsive to phosphodiesterase type 5 inhibitors (PDE5is). Participants were divided into three groups: VED alone, Li-ESWT alone, and combined VED

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June 26, 2025 No Comments

Are Radial Pressure Waves Effective for the Treatment of Moderate or Mild to Moderate Erectile Dysfunction? A Randomized Sham Therapy Controlled Clinical Trial

This 2022 randomized, double-blind, sham-controlled clinical trial assessed the efficacy and safety of radial pressure wave therapy (RPWT) in 80 men with moderate or mild to moderate erectile dysfunction (ED). Participants received six weekly sessions of RPWT or sham therapy, alongside daily sildenafil (25 mg). At six weeks, the mean

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June 26, 2025 No Comments

Low Intensity Shockwave Therapy in Combination with Phosphodiesterase-5 Inhibitors is an Effective and Safe Treatment Option in Patients with Vasculogenic ED who are PDE5i Non-responders: A Multicenter Single-arm Clinical Trial

This 2021 multicenter, open-label prospective study evaluated the safety and efficacy of combining low-intensity extracorporeal shockwave therapy (Li-ESWT) with phosphodiesterase-5 inhibitors (PDE5i) in 109 men with vasculogenic erectile dysfunction (ED) unresponsive to PDE5i monotherapy. Li-ESWT was administered twice weekly for 3 weeks, delivering 3,000 shockwaves per session at 0.25 mJ/mm²

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June 26, 2025 No Comments