Influence of estrogen-progestin treatment on back pain and disability among slim premenopausal women with low lumbar spine bone mineral density. A 2-year placebo-controlled randomized trial

This randomized controlled trial examined the effects of estrogen-progestin therapy on back pain and functional disability in slim premenopausal women with low lumbar spine bone mineral density (BMD). Among 48 participants, those receiving hormone therapy experienced significant reductions in nighttime back pain (p < 0.001) and Oswestry disability scores (p