Well Referenced

Tag: diabetes mellitus

Relations of plasma high-sensitivity C-reactive protein to traditional cardiovascular risk factors

This observational study, published in Atherosclerosis (DOI: 10.1016/s0021-9150(02)00380-5), explored the relationship between plasma high-sensitivity C-reactive protein (hsCRP) levels and traditional cardiovascular risk factors in 908 participants aged 30-79. The study found that hsCRP levels were significantly higher in individuals with hypertension, diabetes, or coronary artery disease, and multiple regression analysis

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June 26, 2025 No Comments

Clinical applications of advanced lipoprotein testing in diabetes mellitus

This review article explores the clinical value of advanced lipoprotein testing in patients with diabetes mellitus, emphasizing that traditional lipid profiles often fail to detect atherogenic subfractions, specifically small, dense LDL particles. Advanced techniques like nuclear magnetic resonance (NMR), gradient gel electrophoresis (GGE), and ultracentrifugation provide greater detail on these

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June 26, 2025 No Comments

Correlations between the level of high-sensitivity C-reactive protein and cardiovascular risk factors in Korean adults with cardiovascular disease or diabetes mellitus: the CALLISTO study

This observational study (CALLISTO) evaluated the correlations between high-sensitivity C-reactive protein (hsCRP) and cardiovascular risk factors in 1,561 Korean adults with cardiovascular disease (CVD) or diabetes mellitus (DM). It found that hsCRP levels significantly correlated with age, BMI, HDL-C, LDL-C/HDL-C ratio, LDL-C/TC ratio, HDL-C/TC ratio, HDL-C/TG ratio, and TC/TG ratio,

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June 26, 2025 No Comments

A comprehensive insight into the effect of glutamine supplementation on metabolic variables in diabetes mellitus: a systematic review

The 2020 systematic review titled “A Comprehensive Insight into the Effect of Glutamine Supplementation on Metabolic Variables in Diabetes Mellitus” (PMID: 32983244) evaluated 19 studies, including clinical and animal research, to assess glutamine’s impact on glycemic control and metabolic health in individuals with diabetes. The review found that glutamine supplementation

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June 26, 2025 No Comments

Possible differential benefits of edetate disodium in post-myocardial infarction patients with diabetes treated with different hypoglycemic strategies in the Trial to Assess Chelation Therapy (TACT)

This study analyzed data from the Trial to Assess Chelation Therapy (TACT) to evaluate whether edetate disodium chelation therapy provided different cardiovascular benefits based on the hypoglycemic treatment used by post-myocardial infarction (MI) patients with diabetes. Among 631 diabetic patients, those receiving insulin therapy experienced a significant reduction in major

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June 26, 2025 No Comments

The Effect of an EDTA-based Chelation Regimen on Patients With Diabetes Mellitus and Prior Myocardial Infarction in the Trial to Assess Chelation Therapy (TACT)

This randomized controlled trial from the Trial to Assess Chelation Therapy (TACT) evaluated the effects of EDTA-based chelation therapy in 1,708 patients aged 50 years or older with a history of myocardial infarction (MI), including 633 with diabetes mellitus. Over five years, chelation therapy significantly reduced major cardiovascular events in

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June 26, 2025 No Comments

The Effect of Lowering Blood Pressure by Magnesium Supplementation in Diabetic Hypertensive Adults With Low Serum Magnesium Levels: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

This randomized controlled trial examined the effects of magnesium chloride (MgCl₂) supplementation on blood pressure and lipid profiles in 82 diabetic hypertensive adults with low serum magnesium levels. Participants received either 2.5 g of MgCl₂ solution daily (providing 450 mg of elemental magnesium) or a placebo for four months while

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June 26, 2025 No Comments

Sildenafil citrate for erectile dysfunction in men with diabetes and cardiovascular risk factors: a retrospective analysis of pooled data from placebo-controlled trials

This meta-analysis evaluated the efficacy and safety of sildenafil citrate in men with erectile dysfunction (ED) and diabetes mellitus (DM), including those with additional cardiovascular (CV) risk factors. The study pooled data from 11 randomized, double-blind, placebo-controlled trials involving 974 men with DM and ED, randomized to receive either placebo

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June 26, 2025 No Comments