Influence of demographic factors and biochemical characteristics on the prostate-specific antigen (PSA) response to testosterone replacement therapy
A cohort study published in the International Journal of Impotence Research (2006) examined how demographic factors and biochemical characteristics affect PSA responses in men undergoing testosterone replacement therapy (TRT). The study involved 3,369 men and found that factors such as age, BMI, baseline testosterone, and initial PSA levels significantly influenced