Tag: cohort study

Influence of demographic factors and biochemical characteristics on the prostate-specific antigen (PSA) response to testosterone replacement therapy

A cohort study published in the International Journal of Impotence Research (2006) examined how demographic factors and biochemical characteristics affect PSA responses in men undergoing testosterone replacement therapy (TRT). The study involved 3,369 men and found that factors such as age, BMI, baseline testosterone, and initial PSA levels significantly influenced

Read More »

Study of adverse outcomes in women using testosterone therapy

This cohort study analyzed data from 2,103 women using testosterone therapy (via implants, tablets, or injections) and 6,309 matched controls to assess adverse health outcomes. The findings indicate that testosterone therapy does not significantly increase the risk of cardiovascular disease, breast cancer, diabetes, or deep vein thrombosis, but it is

Read More »

Plasma sex hormone concentrations and subsequent risk of breast cancer among women using postmenopausal hormones

This prospective cohort study investigated the relationship between plasma sex hormone levels and breast cancer risk in 2,886 postmenopausal women using hormone replacement therapy (HRT). The findings showed that higher plasma levels of estrogens and androgens were significantly associated with an increased risk of breast cancer, with women in the

Read More »