Well Referenced

Tag: blood pressure

Ten-hour time-restricted eating reduces weight, blood pressure, and atherogenic lipids in patients with metabolic syndrome

This observational study investigated the effects of a 10-hour time-restricted eating (TRE) window over 12 weeks in 19 adults with metabolic syndrome (MetS), most of whom were also on statins or antihypertensive medications. TRE led to significant improvements, including an average weight loss of 3.3 kg, reduced waist circumference, BMI,

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June 26, 2025 No Comments

Anthropometric and cardiometabolic effects of polyphenols in people with overweight and obesity: an umbrella review

This umbrella review analyzes the effects of polyphenols on anthropometric measures and cardiometabolic risk factors in individuals with overweight and obesity. Polyphenol supplementation led to significant reductions in body weight, body mass index (BMI), waist circumference, and fasting blood glucose levels. Additionally, improvements were seen in cholesterol levels, blood pressure,

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June 26, 2025 No Comments

Distribution of High-Sensitivity C-Reactive Protein and Its Relationship with Other Cardiovascular Risk Factors in the Middle-Aged Chinese Population

This observational study of 8,389 middle-aged Chinese adults revealed that elevated high-sensitivity C-reactive protein (hs-CRP) levels correlated strongly with age, blood pressure, glucose, BMI, and LDL cholesterol. About 63% of individuals with coexisting hypertension, diabetes, high cholesterol, and obesity had hs-CRP concentrations in the top quartile. These findings underscore hs-CRP’s

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June 26, 2025 No Comments

EDTA chelation reappraisal following new clinical trials and regular use in millions of patients: review of preliminary findings and risk/benefit assessment

This review article reappraises the clinical use of EDTA chelation therapy, highlighting its effectiveness in removing toxic metals such as lead, cadmium, nickel, and aluminum. Based on recent clinical trials, EDTA therapy showed benefits such as a 50% reduction in urinary lead levels and improved systolic blood pressure in cardiovascular

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June 26, 2025 No Comments

Effects of Oral Magnesium Supplementation on Insulin Sensitivity and Blood Pressure in Normo-Magnesemic Nondiabetic Overweight Korean Adults

The study titled “Effects of oral magnesium supplementation on insulin sensitivity and blood pressure in normo-magnesemic nondiabetic overweight Korean adults” examined the effects of daily magnesium supplementation (300 mg as magnesium oxide) over 12 weeks in 155 overweight Korean adults with normal magnesium levels. This randomized, double-blind, placebo-controlled trial found

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June 26, 2025 No Comments

The Effects of L-Carnitine Supplementation on Blood Pressure in Adults: A Systematic Review and Dose-response Meta-analysis

This systematic review and meta-analysis assessed the effects of L-carnitine supplementation on blood pressure (BP) in adults, including 1,412 participants from 22 randomized controlled trials. The results showed no significant reduction in systolic or diastolic blood pressure in the general population. However, a significant reduction in diastolic blood pressure was

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June 26, 2025 No Comments

Methylene Blue: Magic Bullet for Vasoplegia?

This systematic review evaluates the use of methylene blue (MB) in managing vasoplegic shock, particularly in critical care, liver transplantation, and cardiac anesthesia. While MB has shown consistent blood pressure improvement in small studies and case reports, its effect on mortality and oxygen delivery remains inconclusive. The review stresses the

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June 26, 2025 No Comments

Association between testosterone replacement therapy and cardiovascular outcomes: A meta-analysis of 30 randomized controlled trials

This meta-analysis of 30 randomized controlled trials investigated the impact of testosterone replacement therapy (TRT) on cardiovascular outcomes. It found that TRT did not significantly affect cardiovascular mortality but improved cholesterol levels and reduced systolic blood pressure. However, concerns about long-term cardiovascular risks persist. Providers should monitor cardiovascular health during

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June 26, 2025 No Comments

“Beet” the cold: beetroot juice supplementation improves peripheral blood flow, endothelial function, and anti-inflammatory status in individuals with Raynaud’s phenomenon

This randomized controlled trial investigated the effects of nitrate-rich beetroot juice supplementation on individuals with Raynaud’s phenomenon, a condition characterized by reduced blood flow to extremities. The study included 23 participants in a double-blind, randomized crossover design, assessing both acute and chronic (14-day) supplementation. Key findings showed increased peripheral blood

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June 26, 2025 No Comments