Well Referenced

Tag: Atherosclerosis

Berberine, a Herbal Metabolite in the Metabolic Syndrome: The Risk Factors, Course, and Consequences of the Disease

This review article examines the pharmacological effects of berberine, a herbal metabolite, in managing metabolic syndrome and associated conditions like type 2 diabetes, obesity, atherosclerosis, cardiovascular diseases, and polycystic ovary syndrome (PCOS). Berberine improves insulin sensitivity, reduces blood glucose, lowers LDL cholesterol, mitigates inflammation by inhibiting COX-2, and induces apoptosis

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June 26, 2025 No Comments

Low-Level Cadmium Exposure and Atherosclerosis

The article “Low-Level Cadmium Exposure and Atherosclerosis” explores the impact of environmental cadmium exposure on cardiovascular health, emphasizing its role as a pro-atherosclerotic risk factor. It discusses cadmium’s toxicity, its effects on cellular activities, and its association with increased cardiovascular disease (CVD) risk. The authors also highlight potential therapeutic benefits

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June 26, 2025 No Comments

Magnesium Studies

This observational study examined the relationship between dietary magnesium intake and arterial calcification in 2,695 participants free of cardiovascular disease at baseline, with an average age of 53 years. The study found that a 50 mg/day increase in magnesium intake was associated with a 22% reduction in coronary artery calcification

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June 26, 2025 No Comments

MY APPROACH to the use of chelation therapy

This expert opinion article by Dr. Gervasio A. Lamas explores the role of chelation therapy in cardiovascular medicine, discussing its historical use for heavy metal poisoning and its controversial application in treating cardiovascular diseases. The author highlights the hypothesis that chelation therapy may reduce atherosclerosis by removing metal ions that

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June 26, 2025 No Comments

Coronary calcification, coronary disease risk factors, C-reactive protein, and atherosclerotic cardiovascular disease events: the St. Francis Heart Study

This cohort study evaluated the role of coronary calcium scoring in predicting cardiovascular events in asymptomatic individuals, aged 50-70. Over a follow-up period of 4.3 years, the study found that participants with a coronary calcium score ≥100 had a significantly higher risk of cardiovascular events, including coronary artery disease, myocardial

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June 26, 2025 No Comments

Differential association between the progression of coronary artery calcium score and coronary plaque volume progression according to statins: the Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography Imaging (PARADIGM) study

This observational study examined how statins influence the progression of coronary artery calcium (CAC) scores and coronary plaque volume in patients with coronary artery disease. The results indicated that statin therapy slowed the progression of both CAC and plaque volume, with the degree of effect varying by statin type. The

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June 26, 2025 No Comments

Edetate Disodium-Based Treatment for Secondary Prevention in Post-Myocardial Infarction Patients

This article reviews the potential benefits of edetate disodium (a chelating agent) in post-myocardial infarction (MI) patients, particularly those with diabetes, for secondary prevention. The Trial to Assess Chelation Therapy (TACT) demonstrated that edetate disodium therapy led to significant cardiovascular improvements, especially in diabetic patients, showing comparable or superior benefits

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June 26, 2025 No Comments

EDTA Chelation therapy and Cardiovascular issues

EDTA chelation therapy is proposed as a treatment for cardiovascular issues, particularly atherosclerosis, by binding to calcium and other heavy metals in the blood, potentially removing arterial plaque and improving blood flow. While this therapy may benefit individuals with cardiovascular conditions like coronary artery disease, it remains controversial, with limited

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June 26, 2025 No Comments

EDTA chelation therapy meets evidence-based medicine

This article reviews the effectiveness of EDTA chelation therapy in treating cardiovascular disease, particularly for patients with diabetes and coronary artery disease. It highlights the results of the Trial to Assess Chelation Therapy (TACT), which demonstrated that EDTA can reduce cardiovascular events, improve circulation, and decrease arterial plaque, especially in

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June 26, 2025 No Comments