Well Referenced

Tag: aging

Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population

This cohort study investigated the impact of low protein intake on IGF-1 levels, cancer risk, and overall mortality in individuals aged 50-65 and older. It found that reducing protein intake significantly lowered IGF-1 levels and was associated with a decrease in cancer and mortality risk in younger adults (≤65 years),

Read More »
June 26, 2025 No Comments

Relationship between hypoactive sexual desire disorder and aging

This study investigates the prevalence of hypoactive sexual desire disorder (HSDD) across different age groups in Europe and the USA. The results showed that while low sexual desire became more common with age, the prevalence of HSDD remained relatively constant, ranging from 6-13% in Europe and 12-19% in the USA.

Read More »
June 26, 2025 No Comments

Effects of growth hormone–releasing hormone on cognitive function in adults with mild cognitive impairment and healthy older adults: results of a controlled trial

A randomized controlled trial published in Archives of Neurology (PMID: 22869065) examined the effects of growth hormone–releasing hormone (GHRH) on cognitive function in adults with mild cognitive impairment (MCI) and healthy older adults. Over 20 weeks, participants received daily subcutaneous injections of GHRH or a placebo. The study found that

Read More »
June 26, 2025 No Comments

Factors affecting sexuality in older Australian women: sexual interest, sexual arousal, relationships and sexual distress in older Australian women

This cross-sectional study examined the sexual experiences of older Australian women, focusing on sexual activity, interest, arousal, and distress. The findings indicate a decline in sexual activity and interest with age, primarily linked to the loss of intimate partners through separation, divorce, or bereavement. Despite this trend, the study highlights

Read More »
June 26, 2025 No Comments

How sex hormones promote skeletal muscle regeneration

The review article “How sex hormones promote skeletal muscle regeneration” explores the role of androgens and estrogens in skeletal muscle repair, highlighting how aging-related declines in these hormones reduce muscle regeneration efficiency. While androgens are well-known for their anabolic effects, recent findings indicate that estrogens also enhance muscle regeneration by

Read More »
June 26, 2025 No Comments

Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging

This in vitro/animal study examined the effects of thyroid hormone imbalances on healthspan and lifespan using wild-type and Pax8-deficient mice. Findings revealed that both hyperthyroidism and severe hypothyroidism negatively impact overall health and longevity. Mild hypothyroid Pax8+/- mice exhibited increased body weight, insulin resistance, hepatic steatosis, and a higher incidence

Read More »
June 26, 2025 No Comments

Early Life Interventions Can Shape Aging

This study investigates the impact of early-life hormonal interventions on aging using Ames dwarf mice, which are growth hormone (GH) deficient and exhibit extended lifespans. GH injections administered twice daily from two to eight weeks of age normalized several metabolic traits associated with longevity, suggesting that early-life GH therapy may

Read More »
June 26, 2025 No Comments