Intravenous L-carnitine increases plasma carnitine, reduces fatigue, and may preserve exercise capacity in hemodialysis patients
This randomized controlled trial examined the effects of intravenous L-carnitine supplementation on fatigue and exercise capacity in patients with end-stage renal disease (ESRD) undergoing hemodialysis. Patients received L-carnitine at doses of 10 mg/kg, 20 mg/kg, or 40 mg/kg thrice weekly for 24 weeks. While primary analysis showed no significant improvement