This 2021 review article evaluates clinical studies on resveratrol supplementation in overweight and obese individuals. Resveratrol, a polyphenolic compound, exhibits antioxidant, anti-inflammatory, and metabolic regulatory properties. Clinical trials suggest that resveratrol may improve insulin sensitivity, reduce oxidative stress, and modulate adipogenesis through pathways involving SIRT1 activation and AMPK signaling. However,
