Stable Gastric Pentadecapeptide BPC 157 Therapy: Effect on Reperfusion Following Maintained Intra-Abdominal Hypertension (Grade III and IV) in Rats

This preclinical study assessed the therapeutic effects of BPC 157, a stable gastric pentadecapeptide, in a rat model of severe intra-abdominal hypertension (IAH) classified as Grade III and IV. IAH was induced and maintained to simulate critical clinical conditions, followed by reperfusion. Rats treated with BPC 157 exhibited significant improvements