Single nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene are common in US Caucasian and Hispanic American populations

This study examined the prevalence of two common genetic polymorphisms, C677T and A1298C, in the methylenetetrahydrofolate reductase (MTHFR) gene among Caucasian and Hispanic populations in the U.S. The study found high frequencies of these polymorphisms, with notable homozygosity for the C677T SNP (16% in Caucasians, 10% in Hispanics). These genetic