Tag: SNPs

Single nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene are common in US Caucasian and Hispanic American populations

This study examined the prevalence of two common genetic polymorphisms, C677T and A1298C, in the methylenetetrahydrofolate reductase (MTHFR) gene among Caucasian and Hispanic populations in the U.S. The study found high frequencies of these polymorphisms, with notable homozygosity for the C677T SNP (16% in Caucasians, 10% in Hispanics). These genetic

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Nutritional genomics: defining the dietary requirement and effects of choline

This review article explores how genetic variations affect choline metabolism and dietary requirements. It highlights that men and postmenopausal women are more likely to experience liver or muscle dysfunction when deprived of dietary choline, while premenopausal women may resist choline deficiency due to estrogen-induced expression of the PEMT gene, which

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