This 2020 study investigates the anti-metastatic effects of pharmacological ascorbate (P-AscH⁻) in pancreatic ductal adenocarcinoma (PDAC), demonstrating its action via hydrogen peroxide (H₂O₂) generation. In vitro experiments revealed that P-AscH⁻ impairs PDAC cell invasion and matrix degradation, effects reversed by catalase, confirming the role of H₂O₂. In vivo, P-AscH⁻ treatment
