Lymphoma and myeloma cells are highly sensitive to growth arrest and apoptosis induced by artesunate

This 2013 study evaluated the antitumor effects of artesunate, an antimalarial drug, on multiple myeloma and diffuse large B-cell lymphoma (DLBCL) cell lines. Artesunate treatment effectively inhibited cell proliferation and induced apoptosis in these cell lines. The apoptotic response was associated with downregulation of MYC and anti-apoptotic Bcl-2 family proteins,