Tag: IC50

Lymphoma and myeloma cells are highly sensitive to growth arrest and apoptosis induced by artesunate

This 2013 study evaluated the antitumor effects of artesunate, an antimalarial drug, on multiple myeloma and diffuse large B-cell lymphoma (DLBCL) cell lines. Artesunate treatment effectively inhibited cell proliferation and induced apoptosis in these cell lines. The apoptotic response was associated with downregulation of MYC and anti-apoptotic Bcl-2 family proteins,

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The effects of Provera on chemotherapy of uterine cancer cell lines

A study examined the effects of Provera, a progestational compound, on the efficacy of chemotherapy in various uterine cancer cell lines. Using the ATP chemosensitivity assay and flow cytometry, researchers analyzed progesterone-receptor (PR)-positive (AE7 and ECC1) and PR-negative (HEC1A, HEC1B, AN3, and SKUT1B) cell lines. The findings showed that Provera

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