Intradiscal O2O3: Rationale, Injection Technique, Short- and Long-term Outcomes for the Treatment of Low Back Pain Due to Disc Herniation

This article examines the use of intradiscal oxygen-ozone (O2O3) therapy for treating low back pain (LBP) caused by disc herniation, particularly in cases that do not respond to conservative treatments. It highlights the safety and efficacy of O2O3 therapy, which reduces disc volume through dehydration and offers significant pain relief