Incretin Hormones and the Satiation Signal

This 2013 review discusses the role of incretin hormones, particularly glucagon-like peptide-1 (GLP-1), in regulating appetite and inducing satiation. GLP-1 is secreted by intestinal L-cells in response to nutrient intake and acts through both peripheral and central pathways to promote feelings of fullness. It slows gastric emptying, enhances insulin secretion,