Hyperbaric oxygen for treatment of long COVID-19 syndrome (HOT-LoCO): protocol for a randomised, placebo-controlled, double-blind, phase II clinical trial

This study investigates the efficacy of hyperbaric oxygen therapy (HBOT) as a treatment for long COVID-19 symptoms. The trial aims to assess whether HBOT improves health-related quality of life (HRQoL) in patients suffering from long COVID-19, comparing its effects to a placebo. Secondary objectives include evaluating improvements in endothelial function,