Growth response to growth hormone-releasing hormone(1-29)-NH2 compared with growth hormone

This study compared the effectiveness of growth hormone-releasing hormone (GHRH(1-29)-NH₂) with standard growth hormone (GH) therapy in promoting growth in children with hypothalamic growth hormone deficiency (GHD). High-dose GHRH(1-29)-NH₂ significantly increased height velocity, comparable to GH treatment, but had no effect on bone age development. GHRH(1-29)-NH₂ did not induce GH