Comparison of hyaluronic acid and PRP intra-articular injection with combined intra-articular and intraosseous PRP injections to treat patients with knee osteoarthritis

This randomized controlled trial compared the effectiveness of intra-articular platelet-rich plasma (PRP) injections, hyaluronic acid (HA) injections, and a combination of intra-articular and intraosseous PRP injections in treating knee osteoarthritis (OA). The study found that the combined PRP treatment resulted in superior outcomes, with significant reductions in pain and improvements