Well Referenced

Tag: Functional Improvement

Extracorporeal Shock Wave Therapy for the Treatment of Osteoarthritis: A Systematic Review and Meta-Analysis

This 2020 systematic review and meta-analysis evaluated the efficacy and safety of extracorporeal shock wave therapy (ESWT) in treating osteoarthritis (OA). The analysis included randomized controlled trials comparing ESWT with other treatments such as placebo, corticosteroids, hyaluronic acid, medications, ultrasound, kinesiotherapy, moxibustion, acupotomy surgery, platelet-rich plasma, fumigation, and manipulation. ESWT

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June 26, 2025 No Comments

Correction: Comparison between intra-articular ozone and placebo in the treatment of knee osteoarthritis: A randomized, double-blinded, placebo-controlled study

This 2024 correction addresses the original 2017 randomized, double-blinded, placebo-controlled trial that evaluated the efficacy of intra-articular ozone injections in patients with knee osteoarthritis (KOA). The study involved 98 participants who received either ozone (20 μg/mL) or placebo injections over 8 weeks. Outcomes measured included pain (VAS), function (WOMAC, Lequesne

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June 26, 2025 No Comments

Long-term effects of intra-articular oxygen-ozone therapy versus hyaluronic acid in older people affected by knee osteoarthritis: A randomized single-blind extension study

This study investigates the long-term effectiveness and safety of intra-articular oxygen-ozone (O₂O₃) therapy compared to hyaluronic acid injections for treating knee osteoarthritis in older adults. A total of 60 participants, aged 60 or older, with knee osteoarthritis were randomly assigned to receive four weekly injections of either O₂O₃ or hyaluronic

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June 26, 2025 No Comments

Comparative evaluation of oxygen-ozone therapy and combined use of oxygen-ozone therapy with percutaneous intradiscal radiofrequency thermocoagulation for the treatment of lumbar disc herniation

This randomized controlled trial compared the effectiveness of oxygen-ozone therapy alone versus a combination of oxygen-ozone therapy and percutaneous intradiscal radiofrequency thermocoagulation (PIRFT) for the treatment of lumbar disc herniation. The study showed that both treatments significantly reduced pain and disability, but the combination therapy (ozone-PIRFT) led to superior outcomes

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June 26, 2025 No Comments

Comparison of hyaluronic acid and PRP intra-articular injection with combined intra-articular and intraosseous PRP injections to treat patients with knee osteoarthritis

This randomized controlled trial compared the effectiveness of intra-articular platelet-rich plasma (PRP) injections, hyaluronic acid (HA) injections, and a combination of intra-articular and intraosseous PRP injections in treating knee osteoarthritis (OA). The study found that the combined PRP treatment resulted in superior outcomes, with significant reductions in pain and improvements

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June 26, 2025 No Comments

Intramuscular paravertebral oxygen-ozone therapy for chronic neck pain and low back pain: evaluation of 6-month clinical outcomes

This study evaluates the effects of oxygen-ozone therapy for chronic neck and low back pain, using intramuscular paravertebral injections over a 6-month period. It found significant improvements in pain reduction, disability, and quality of life, with a reduction in analgesic drug consumption. The therapy was safe and minimally invasive, offering

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June 26, 2025 No Comments

Platelet rich plasma therapy versus other modalities for treatment of plantar fasciitis: A systematic review and meta-analysis

This meta-analysis compared platelet-rich plasma (PRP) therapy with other treatments for plantar fasciitis, finding that PRP significantly reduced pain and improved functional outcomes compared to extracorporeal shock wave therapy (ESWT) and corticosteroid injections (CSI). With a pooled sample of 1,356 patients across 21 RCTs, PRP showed a superior effect in

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June 26, 2025 No Comments

Does Menopausal Hormone Therapy, Exercise, or Both Improve Pain and Function in Postmenopausal Women With Greater Trochanteric Pain Syndrome? A 2 × 2 Factorial Randomized Clinical Trial

This randomized controlled trial investigated the effects of menopausal hormone therapy (MHT), exercise, and their combination on pain and function in postmenopausal women with Greater Trochanteric Pain Syndrome (GTPS). Results showed that both MHT and placebo, when combined with either tendon-specific or sham exercise plus education, led to pain reduction

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June 26, 2025 No Comments