The meta-analysis titled "Combined T4 + T3 Therapy Versus T4 Monotherapy Effect on Psychological Health in Hypothyroidism" (Clinical Endocrinology, 2022, PMID: 35445422) evaluated the psychological effects of combined levothyroxine (T4) and liothyronine (T3) therapy compared to T4 monotherapy across nine randomized controlled trials involving 1,210 hypothyroid patients. The analysis found
