Well Referenced

Tag: depression

Parental Communication About Body Weight and Adolescent Health: The Role of Positive and Negative Weight-Related Comments

This 2023 study examined how positive and negative weight-related comments from mothers and fathers affect adolescent health and well-being. Surveying 2,032 U.S. adolescents aged 10–17, researchers found that frequent negative comments from parents were linked to higher levels of depression, unhealthy weight control behaviors, and weight bias internalization. Conversely, positive

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June 26, 2025 No Comments

Neuropsychiatric Adverse Effects of Centrally Acting Antiobesity Drugs

This 2011 review examines the neuropsychiatric side effects associated with centrally acting antiobesity medications. Drugs targeting monoamine systems, such as sibutramine, bupropion, and tesofensine, commonly induce insomnia but may also offer mood-enhancing benefits for patients with comorbid depression or anxiety. Agents affecting μ-opioid receptors, like naltrexone and its combination with

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June 26, 2025 No Comments

Natural products, micronutrients, and nutraceuticals for the treatment of depression: A short review

This 2017 review article explores the potential of natural compounds, micronutrients, and nutraceuticals in managing depression. It highlights the limitations of conventional antidepressants, such as delayed onset and adverse effects, and discusses alternative treatments. The review examines various natural substances, including green tea catechins, anthocyanins, cocoa extracts, resveratrol, omega-3 fatty

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June 26, 2025 No Comments

St. John’s wort: a new alternative for depression?

This 1999 review article evaluates the efficacy, safety, and potential drug interactions of St. John’s wort (Hypericum perforatum) as an alternative treatment for depression. Analyzing nine clinical trials, including four large-scale studies, the review found that St. John’s wort was more effective than placebo and comparable to standard antidepressants in

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June 26, 2025 No Comments

Dietary creatine intake and depression risk among U.S. adults

This 2020 cross-sectional study analyzed data from the 2005–2012 National Health and Nutrition Examination Survey (NHANES) to investigate the association between dietary creatine intake and depression risk among 22,692 U.S. adults aged ≥20 years. Depression was assessed using the Patient Health Questionnaire-9 (PHQ-9), with a score ≥10 indicating depression. Dietary

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June 26, 2025 No Comments

A Double-Blind, Randomized Pilot Trial of Chromium Picolinate for Binge Eating Disorder

This 6-month double-blind, placebo-controlled pilot study evaluated the effects of chromium picolinate supplementation on binge eating disorder (BED) in 24 overweight adults. Participants were randomized to receive either 1000 μg/day (high dose), 600 μg/day (moderate dose) of chromium picolinate, or placebo. Both chromium groups exhibited significant reductions in fasting glucose

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June 26, 2025 No Comments

Essential elements in depression and anxiety. Part II

This 2015 review examines the roles of copper, selenium, manganese, iodine, and vanadium in the pathophysiology of depression and anxiety. The study discusses how these trace elements, as cofactors for enzymes involved in neurotransmitter synthesis and antioxidant defense, may influence mental health. For instance, copper is essential for dopamine and

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June 26, 2025 No Comments

5-Hydroxytryptophan: A Clinically-Effective Serotonin Precursor

This 1998 review by Timothy C. Birdsall, N.D., explores the clinical efficacy of 5-hydroxytryptophan (5-HTP) as a serotonin precursor. 5-HTP, derived from L-tryptophan or extracted from Griffonia simplicifolia seeds, bypasses the rate-limiting step of serotonin synthesis and crosses the blood-brain barrier without a transport molecule. It is well absorbed orally,

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June 26, 2025 No Comments