The Oxygen-Ozone Adjunct Medical Treatment According to the Protocols from the Italian Scientific Society of Oxygen-Ozone Therapy: How Ozone Applications in the Blood Can Influence Clinical Therapy Success via the Modulation of Cell Biology and Immunity

This 2023 review by Chirumbolo et al. outlines the protocols established by the Italian Scientific Society of Oxygen-Ozone Therapy (SIOOT) for administering oxygen-ozone therapy (OOT) via blood-based methods such as major autohemotherapy (MAH). The authors discuss how low-dose ozone interacts with blood components to generate reactive oxygen species and lipid