The Impact of Plasma Vitamin C Levels on the Risk of Cardiovascular Diseases and Alzheimer’s Disease: A Mendelian Randomization Study

This 2021 Mendelian randomization study assessed the causal relationship between plasma vitamin C levels and the risk of nine cardiovascular diseases (CVDs) and Alzheimer's disease (AD). Utilizing 11 single-nucleotide polymorphisms (SNPs) associated with plasma vitamin C levels from a genome-wide meta-analysis (N = 52,018), the researchers performed analyses using fixed-effects