Vitamin D, sunlight, and the epidemiology of prostate cancer

This 2012 review examines the relationship between vitamin D, sunlight exposure, and prostate cancer risk. Ecological studies indicate an inverse correlation between ultraviolet (UV) radiation levels and prostate cancer mortality. Human prostate cells possess receptors for 1,25-dihydroxyvitamin D, which exhibits anticancer effects in vitro and in animal models. While some