This 2004 case-control study by Chevrier et al. investigated the association between ozonated drinking water and bladder cancer risk in France. Analyzing data from 281 cases and 272 controls with at least 70% residential exposure data over 30 years, the study found that longer exposure to ozonated water correlated with
This 2020 cross-sectional study analyzed data from the 2005–2012 National Health and Nutrition Examination Survey (NHANES) to investigate the association between dietary creatine intake and depression risk among 22,692 U.S. adults aged ≥20 years. Depression was assessed using the Patient Health Questionnaire-9 (PHQ-9), with a score ≥10 indicating depression. Dietary
This 2018 review examines the antiviral properties of tea catechins, particularly epigallocatechin gallate (EGCG), against influenza and common cold viruses. Experimental studies indicate that catechins inhibit viral adsorption, replication, and neuraminidase activity, and enhance immune responses. Epidemiological studies suggest that regular green tea consumption and catechin-based gargling may reduce the
This 2024 cohort study analyzed data from 32,995 U.S. adults (mean age 46.7 years; 50.1% women) from the NHANES 1999–2018 cycles to evaluate trends in Body Roundness Index (BRI) and its association with all-cause mortality. BRI, which incorporates waist circumference and height, increased from 4.80 to 5.62 over the study
This 2021 comprehensive review article provides an in-depth analysis of Lyme disease, a tick-borne illness caused by Borrelia burgdorferi sensu lato complex. The disease is prevalent across the Northern Hemisphere and is transmitted by ticks from the Ixodes ricinus complex. The article discusses the increasing global incidence of Lyme disease,
This 2011 letter to the editor critiques a prior case report suggesting a link between phentermine monotherapy and pulmonary arterial hypertension (PAH). The authors argue that the case likely represents idiopathic PAH rather than being induced by phentermine. They reference epidemiological studies indicating no significant association between phentermine use and
This 2017 CDC report analyzed U.S. cancer registry data from 2005 to 2014, focusing on 13 cancers linked to overweight and obesity, including postmenopausal breast, colorectal, endometrial, pancreatic, and liver cancers. In 2014, approximately 631,000 cases (40% of all cancers) were associated with excess body weight. Incidence rates were higher
This 2012 review examines the relationship between vitamin D, sunlight exposure, and prostate cancer risk. Ecological studies indicate an inverse correlation between ultraviolet (UV) radiation levels and prostate cancer mortality. Human prostate cells possess receptors for 1,25-dihydroxyvitamin D, which exhibits anticancer effects in vitro and in animal models. While some
This 2020 epidemiological study analyzed glioblastoma multiforme (GBM) cases in Malta from 2008 to 2017. The incidence of GBM increased significantly from 0.73 to 4.49 per 100,000 people over the decade (p ≤ 0.001). Factors contributing to this rise may include an aging population, improved diagnostic techniques, and environmental exposures.
This multicenter retrospective cohort study analyzed 611 patients who remained cancer-free for at least two years following treatment for histologically confirmed small-cell lung cancer (SCLC). The study assessed the incidence of second primary cancers (SPCs) in this population. Findings revealed that the overall risk of SPCs was 3.5 times higher
