Responses of Melanoma Cells to Photobiomodulation Depend on Cell Pigmentation and Light Parameters

This 2022 preclinical study investigated the effects of photobiomodulation (PBM) on melanoma cells with varying pigmentation levels. The researchers found that near-infrared (NIR) irradiation at 30 J/cm² increased invasiveness in pigmented melanoma cells, whereas all light doses inhibited cell migration. Conversely, a high dose (150 J/cm²) of red laser light