This 2015 review by Sánchez et al. discusses the dual antioxidant and anti-inflammatory roles of melatonin in combating oxidative stress. Melatonin not only scavenges reactive oxygen and nitrogen species directly but also stimulates antioxidant enzymes like superoxide dismutase, glutathione peroxidase, and catalase. Due to its amphiphilic properties, melatonin effectively crosses
