A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue

This randomized, double-blind, placebo-controlled study evaluated the efficacy of SHR-5, a standardized extract of Rhodiola rosea, in reducing stress-related fatigue. The study included 60 participants aged 20-55 who were diagnosed with fatigue syndrome. After 28 days, the SHR-5 group showed significant improvements in fatigue, cortisol response, and attention performance compared