This study investigated the association between blood glucose levels within the normal range (
This longitudinal study evaluated the impact of dietary choline intake on cognitive performance and brain structure in 1,391 dementia-free individuals (mean age 61) from the Framingham Offspring Cohort. Dietary data were collected via food frequency questionnaires, and participants underwent neuropsychological testing and MRI imaging. Results indicated that higher concurrent choline
This 2015 randomized controlled trial examined the acute effects of a single dose of a multivitamin, mineral, and herbal (MVMH) supplement on mood and cognitive performance in 76 healthy women aged 50 to 75. Results showed significant improvements in mood—specifically reduced mental stress and increased calmness—within one to two hours
This randomized, double-blind, placebo-controlled study evaluated the efficacy of SHR-5, a standardized extract of Rhodiola rosea, in reducing stress-related fatigue. The study included 60 participants aged 20-55 who were diagnosed with fatigue syndrome. After 28 days, the SHR-5 group showed significant improvements in fatigue, cortisol response, and attention performance compared
This cohort study examined the association between dietary choline intake, particularly phosphatidylcholine, and dementia risk in 2,497 middle-aged and older men in eastern Finland over a 21.9-year follow-up. Men in the highest quartile of phosphatidylcholine intake had a 28% lower risk of developing dementia compared to those in the lowest
This observational study examined the effects of hormone replacement therapy (HRT) on cognitive performance in postmenopausal women, analyzing data from the Danish MONICA study. It found that current users of HRT experienced less decline in concentration and visuomotor function compared to non-users. Women who started HRT during the study demonstrated
This review explores the critical role of testosterone in women’s health, highlighting its effects on sexual desire, cardiovascular function, cognitive performance, and musculoskeletal health. While observational studies suggest potential cardiovascular benefits, a definitive link between endogenous testosterone and disease risk remains unclear. Clinical trials indicate testosterone therapy may enhance cognitive
This randomized controlled trial evaluated the effects of a nutraceutical formulation (NF) containing folate, alpha-tocopherol, B12, S-adenosyl methionine, N-acetyl cysteine, and acetyl-L-carnitine on cognitive performance in individuals with mild cognitive impairment (MCI). Thirty-four participants received either the NF or a placebo for six months, followed by a six-month open-label extension
