Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E: the St. Francis Heart Study randomized clinical trial

This randomized controlled trial evaluated the effects of atorvastatin (20 mg daily), vitamin C (1 g daily), and vitamin E (1,000 U daily) on coronary artery calcification and cardiovascular events in 1,005 asymptomatic adults aged 50 to 70 with elevated coronary calcium scores. Over a mean follow-up of 4.3 years,